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These reporters are mostly primarily based on FRET (fluorescence resonance energy transfer), along with a review about the various constructs that have been intended to report spatiotemporal signaling of Rho family members GTPase members has been read more...

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This query was (at least partially) answered through the acquiring the cis-Golgi protein GM130 is involved in MT formation [24]. GM130 binds to AKAP450, a centrosomal protein, and therefore read more...

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four.3. Nucleation of MicrotubulesThe construction along with the positioning on the Golgi are dependent to the microtubule (MT) cytoskeleton, which was initially demonstrated by showing the Golgi fragmented into many ministacks on treatment metho read more...

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Like Cdc42, also a number of its downstream effectors have been shown to localize towards the Golgi and to be concerned in cell migration. Signals from surface receptors by way of Rac and Cdc42 regulate read more...